Lexus GX Rough Running

Rough running on a hybrid GX with those kilometers could be a few things. Have you checked the usual suspects like air filter, spark plugs, or even for engine misfires? Fuel injectors could also be playing up.

Plugs and air filter were done recently. I haven't checked for misfires specifically. How would a small exhaust leak cause this kind of issue?

If it's pre-cat, the O2 sensor readings could be skewed, messing with the fuel trim and causing the jerking. Those readings could also trigger those specific CEL codes. Still, I'd hook it up to a diagnostic machine and then check the leak if you really suspect it. Better let professionals have a look.

Thanks. Turns out you were spot on about the exhaust leak messing with the O2 sensor. Shop found and fixed it for 265€. Runs like new now.